L'Ecole de Nogent: the contributions of Etienne Wolff and Nicole Le Douarin.
نویسندگان
چکیده
We retrace here the foundation of the "Nogent School". What were its main scientific orientations? Two fields of research dominated Etienne Wolff's work: Experimental Teratology and Intersexuality. Nicole Le Douarin's work , in one sense, started with a remarkable tool which is the quail / chick marker system. She applied this system to the study of in vivo migration of cells during embryonic life, i.e.neural crest cells and lymphoid progenitors. This article revisits some of these fundamental aspects.
منابع مشابه
Laudatio Nicole Le Douarin
On behalf of the ISDB it is my privilege and honour to introduce to you the Ross G. Harrison prize winner, Nicole Le Douarin. It is hard fo me to imagine a more deserving recipient. The prize is named after Ross Harrison, a founding father of tissue culture and of hetero-specific grafting. In his experiments, Ross Harrison described a number of chimerae in which heads of dark Rana silvatica lav...
متن کاملCellular dynamics and molecular control of the development of organizer-derived cells in quail-chick chimeras.
Malformations affecting the nervous system in humans are numerous and various in etiology. Many are due to genetic deficiencies or mechanical accidents occurring at early stages of development. It is thus of interest to reproduce such human malformations in animal models. The avian embryo is particularly suitable for researching the role of morphogenetic movements and genetic signaling during e...
متن کاملBrain switching: studying evolutionary behavioral changes in the context of individual brain development.
Working together at Nogent, Marie-Aimee Teillet, Nicole Le Douarin and the author successfully developed an extension of the quail-chick transplant technique for relating species brain cell differences to behavioral differences. This article reviews the application of the technique to species differences in motor behavior (crowing) and auditory perceptual preferences. Interspecies brain transpl...
متن کاملNicole Le Douarin and Charles Ordahl's Experiments on the Developmental Lineages of Somites
Through various studies developmental biologists have been able to determine that the muscles of the back, ribs, and limbs derive from somites [5]. Somites are blocks of cells that contain distinct sections that diverge into specific types (axial or limb) of musculature and are an essential part of early vertebrate development. For many years the musculature of vertebrates was known to derive f...
متن کاملAntero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesis.
This review is dedicated to the work on chick digestive tract organogenesis that Nicole Le Douarin performed as a PhD student under the direction of Etienne Wolf. I discuss how she laid the grounds for future work by establishing fate maps at somitic stages, by describing morphogenetic movements between germ layers and by pointing to signaling events between endoderm and mesoderm. Her inspiring...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The International journal of developmental biology
دوره 49 2-3 شماره
صفحات -
تاریخ انتشار 2005